Shiguang Yu Selected Research

Therapeutics

1/2015	NOD.H-2h4 mice: an important and underutilized animal model of autoimmune thyroiditis and Sjogren's syndrome.
10/2013	Agonistic anti-CD40 promotes early development and increases the incidence of severe thyroid epithelial cell hyperplasia (TEC H/P) in CD4-/- mice.
4/2013	Agonistic anti-CD40 induces thyrocyte proliferation and promotes thyroid autoimmunity by increasing CD40 expression on thyroid epithelial cells.
4/2012	Transient depletion of B cells in young mice results in activation of regulatory T cells that inhibit development of autoimmune disease in adults.

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Shiguang Yu Research Topics

Disease

6	Autoimmune Diseases (Autoimmune Disease) 12/2017 - 10/2007
4	Hyperplasia 10/2013 - 01/2006
4	Autoimmune Thyroiditis (Lymphomatous Thyroiditis) 05/2010 - 10/2002
3	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 01/2017 - 12/2013
3	Fibrosis (Cirrhosis) 10/2013 - 08/2008
2	Neuroinflammatory Diseases 01/2020 - 01/2017
2	Multiple Sclerosis 01/2017 - 08/2014
2	Thyroid Diseases (Thyroid Disease) 01/2015 - 10/2007
2	Inflammation (Inflammations) 06/2008 - 10/2007
1	Body Weight (Weight, Body) 01/2021
1	Sjogren's Syndrome (Sjogren Syndrome) 01/2015
1	Neoplasms (Cancer) 04/2013
1	B-Cell Lymphoma (Lymphoma, B Cell) 04/2012
1	Disease Progression 06/2008
1	Graves Disease (Basedow Disease) 10/2007
1	Skin Diseases (Skin Disease) 01/2002

Drug/Important Bio-Agent (IBA)

3	RNA-Binding Proteins (RNA-Binding Protein)IBA 01/2020 - 12/2013
3	CytokinesIBA 01/2015 - 10/2007
2	Transforming Growth Factor beta (TGF-beta)IBA 05/2010 - 08/2008
2	Thyroglobulin FDA Link 05/2010 - 06/2008
2	IodineIBA 10/2007 - 01/2006
1	hydroxide ionIBA 01/2021
1	Vitamin D FDA LinkGeneric 01/2021
1	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 12/2017
1	CC ChemokinesIBA 01/2017
1	AntigensIBA 01/2015
1	Immunologic Factors (Immunomodulators)IBA 08/2014
1	ammonium trichloro(dioxoethylene-O,O'-)tellurate (AS 101)IBA 08/2014
1	Interleukin-17 (Interleukin 17)IBA 12/2013
1	AutoantibodiesIBA 06/2008
1	Interferon-gamma (Interferon, gamma)IBA 10/2007
1	gamma-AIBA 10/2007
1	Drinking WaterIBA 02/2006
1	Interleukin-4 (Interleukin 4)IBA 10/2002
1	AntioxidantsIBA 01/2002
1	Vitamin E FDA LinkGeneric 01/2002

Therapy/Procedure

4	Therapeutics 01/2015 - 04/2012
1	Immunotherapy 06/2008